|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Osthole treatment alleviates atopic dermatitis through directly down-regulating TSLP production from keratinocytes.
|
30825337 |
2019 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
DNA demethylation of a specific regulatory region of the TSLP gene may contribute to TSLP overexpression in skin lesions in patients with AD.
|
24341479 |
2014 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In addition, AS significantly suppressed serum levels of histamine and IgE, while Bu-OH significantly suppressed serum levels of histamine, IgE, thymic stromal lymphopoietin (TSLP), interleukin (IL)-4 and IL-6, and DEQA significantly suppressed serum levels of histamine, IgE, TSLP and IL-4 in DNFB-induced AD mice.
|
29740850 |
2018 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
TSLP was highly expressed by epithelial cells, especially keratinocytes from patients with atopic dermatitis.
|
12055625 |
2002 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Skin-specific overexpression of TSLP resulted in an AD-like phenotype, with the development of eczematous lesions containing inflammatory dermal cellular infiltrates, a dramatic increase in Th2 CD4+ T cells expressing cutaneous homing receptors, and elevated serum levels of IgE.
|
16103410 |
2005 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
This role is supported by the finding that TSLP expression is upregulated in keratinocytes of atopic dermatitis skin lesions and in bronchial epithelial cells in asthma.
|
20146705 |
2010 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Western blot analysis showed decreased expression of thymic stromal lymphopoietin (TSLP), an AD cytokine, in the rabbit AD-like skin.
|
28667471 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
TSLP expression is enhanced in lesions with atopic dermatitis, and is a therapeutic target.
|
23688403 |
2013 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Dermal transgenic expression of IL-13 causes an AD-like phenotype with fibrosis and increased TSLP.
|
21576506 |
2011 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In addition, cordycepin reduced thymic stromal lymphopoietin (TSLP), interleukin (IL)-4, IL-6, and tumor necrosis factor-α levels in the serum of AD mice.
|
30183461 |
2018 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Oral administration of physcion improved the severity of 2,4-dinitrochlorobenzene-induced AD-like lesional skin through reducing infiltration of inflammatory cells and mast cells, and the protein and mRNA levels of TSLP, IL-4, and IL-6 in the lesional skin tissues.
|
30991764 |
2019 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
ΔNp73 was abundantly expressed in the AD epidermis and increased the release of TSLP via NF-κB activation.
|
28655470 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
CD1a expression is up-regulated by TSLP (thymic stromal lymphopoietin) at levels observed in the skin of patients with atopic dermatitis, and the response is dependent on PLA2G4A.
|
29273672 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.
|
28224996 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to examine the relationships between the degree of TSLP expression in the skin and the severity of AD, eruption type and epidermal barrier function using a non-invasive method in a sizeable group of the patients.
|
23379440 |
2013 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Thus, we investigated that Niram might ameliorate AD through regulation of TSLP.
|
25461559 |
2014 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
These characteristics of AD-like lesions and thymic stromal lymphopoietin (TSLP) expression peaked at Day 1 of the establishment of our model and gradually alleviated over time.
|
30042397 |
2018 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The β-sitosterol attenuates atopic dermatitis-like skin lesions through down-regulation of TSLP.
|
24510054 |
2014 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The study also suggested that melatonin enhanced the expression of Nrf2, up-regulated the antioxidant genes HO-1 and NQO1, reduced the levels of oxidative stress and TSLP, and alleviated allergic dermatitis.
|
27871981 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Skin barrier disruption could induce thymic stromal lymphopoietin (TSLP) expression, and the expression of TSLP was increased in lesions of atopic dermatitis (AD)-like GVHD and lichen planus (LP)-like GVHD.
|
28584210 |
2017 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In mice, both EGF and pimecrolimus groups showed less erythema with significantly reduced inflammation and decreased expression of thymic stromal lymphopoietin.EGF relieved <i>S. aureus</i>-induced inflammation and AD-like skin lesions in Nc/Nga mice.
|
29862299 |
2018 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In line with the in vitro results, Rh2 inhibited TSLP levels in AD mice via regulation of an underlying mechanism involving the nuclear factor κB pathways.
|
31817146 |
2019 |
|
Dermatitis, Atopic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
TSLP is highly expressed in keratinocytes under inflammatory conditions, which suggests that it may play a critical role in the development of skin diseases, such as atopic dermatitis.
|
29310423 |
2018 |
|
Glomerulonephritis, Membranoproliferative
|
0.510 |
AlteredExpression
|
disease |
BEFREE |
Mice transgenic for thymic stromal lymphopoietin (TSLP), under regulation of the lymphocyte-specific promoter Lck, develop cryoglobulinemia and membranoproliferative glomerulonephritis (MPGN) similar to the disease in patients.
|
21814168 |
2011 |
|
Asthma
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.
|
28224996 |
2017 |